We get this question a LOT. You’ve been bit by a tick, your primary ordered a “megadose” of Doxy… is it sufficient? According to Dr. Bellovin, a prophylactic dose is advised but such a one-200mg dose may be inadequate. “Such treatment could render a patient seronegative by blunting the immune response and only partially eradicating the spirochetes, while permitting the development of resistance and a more virulent infection with an atypical presentation” Info retrieved from Lyme Action Network ☀️ remember, according to the CDC, a bulls eye rash with no known tick bite IS a positive case. No further testing is necessary. However, please remember ticks can carry co infections, which warrant further testing.